Mario must jump over three barrels that are side by side. Mario must jump over two barrels that start the level falling from an edge. Mario must jump over two barrels that are a bit apart. Mario must jump over two barrels that are very near each other. However, he starts on the bottommost platform. Mario starts right on the tip of the top platform. Mario must remove the topmost bolt in the right side of the stage. Mario starts holding the hammer and must break 2 barrels. NES Remix contains challenges based upon the following games: The game also allows the player to quickly access the Nintendo eShop page for any of the games featured.

The game also incorporates stamps after clearing each level, the player is given a certain number of Bits based upon the conditions on which they cleared the stage, and collecting a certain number of Bits unlocks a stamp that represents a character or an item of the game. The game originally featured Miiverse integration before the shutdown on November 2017, in that players could share their level clear times with other players, and make posts to Miiverse which could be viewed and liked by other players in-game. These stars are required to unlock the Remix levels. After clearing each stage, the player is given a ranking of one to three stars based upon their clear time if the player clears in a low enough time, the three stars become rainbow stars. Losing all of them results in a game over. During each stage, the player is given a certain number of hearts as 'life' if the player dies at any point in the game, they 'Miss' and lose one heart. backwards as Luigi, or playing Donkey Kong as Link. Examples include beating a stage from Super Mario Bros. NES Remix contains sixteen NES games remixed with new challenges.

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